The article “Model-guided development of an evolutionarily stable yeast chassis” was recently published in Molecular Systems Biology. This work presents a proof-of-concept for pre-optimized platform strains for producing a family of compounds and is a result of the ERA-IB DeYeast Library project with contributions from Paulo Maia from SilicoLife.
The article “Metabolic engineering strategies for butanol production in Escherichia coli” was recently published in Biotechnology and Bioengineering. This review, with contributions from SilicoLife, focuses on the bioproduction of butanol from a historical and theoretical perspective and exploits the outstanding challenges.
The “MEMOTE for standardized genome-scale metabolic model testing” was recently published in Nature Biotechnology. This work, providing quality control and continuous quality assurance of metabolic models with tools and best practices already used in software development, is a community-wide effort including contributions from Paulo Maia and Paulo Vilaça from SilicoLife.
The paper “Comparison of pathway analysis and constraint-based methods for cell factory design” was recently published on BMC Bioinformatics. This work has contributions from SilicoLife together with researchers from University of Minho and ITQB-NOVA.
The paper “Turnover Dependent Phenotypic Simulation: A Quantitative Constraint-Based Simulation Method That Accommodates All Main Strain Design Strategies” was recently published on ACS Synthetic Biology. This work has contributions from SilicoLife together with researchers from University of Minho, Chalmers University of Technology, Novo Nordisk Foundation Center for Biosustainability and ITQB-NOVA.
New reviewed by SilicoLife published on Frontiers in Microbiology: A Review of Dynamic Modeling Approaches and Their Application in Computational Strain Optimization for Metabolic Engineering This article is part of the work being developed by the ESR Osvaldo Kim in the ITN SymBioSys.
Actinobacillus succinogenes genome-scale metabolic model developed by SilicoLife published on BMC Systems Biology, read the complete article here: Reconstruction of a genome-scale metabolic model for Actinobacillus succinogenes 130Z
Information retrieval tool for biomedical patents developed in collaboration with SilicoLife published on Computer Methods and Programs in Biomedicine, read the complete article here: Development of an information retrieval tool for biomedical patents