Data-driven Enzyme Design

Enzymes are natural molecular machines that can perform the amazing feat of enabling and accelerating chemical reactions without themselves being consumed in the process. All living organisms on Earth depend on enzymes to process nutrients, to grow and to reproduce. Thanks to the development of modern biotechnology, enzymes can also be produced in large quantities and employed to speed up all kinds of industrially important reactions, ranging from stain removal by detergents to production of food, feed, and biomaterials.

This hackathon promoted by DuPont Industrial Biosciences is organized as part of the Dutch Data Science Week, more info here. The company routinely screen thousands of enzymes to obtain models of the relationship between the sequence of amino acid residues that make up the enzyme, its 3D structure, and the observed performance.

A team of scientists from SilicoLife is participating in this event to explore techniques like deep learning to support enzyme optimization process.